Evidence-based recommendations on lenvatinib (Kisplyx) with everolimus for previously treated advanced renal cell carcinoma in adults.
Evidence-based recommendations on glecaprevir–pibrentasvir (Maviret) for treating chronic hepatitis C in adults.
Evidence-based recommendations on ceritinib (Zykadia) for untreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer in adults.
This guideline covers diagnosing and managing age-related macular degeneration (AMD) in adults. It aims to improve the speed at which people are diagnosed and treated to prevent loss of sight.
This document describes an operational definition of sepsis and supports the implementation of the NICE guidelines on the identification and treatment of sepsis.
Improving health outcomes, preventing serious illness, providing convenient, timely and cost effective care, and avoiding the unnecessary use of acute hospitals, is a shared goal across the NHS, and requires a radical re-think about how and where care is delivered,
This guideline covers recognising and diagnosing autism spectrum disorder in children and young people from birth up to 19 years. It also covers referral. It aims to improve the experience of children, young people and those who care for them. In
NICE has assessed 2 point-of care coagulometers to help the NHS decide whether to use these products. They are called CoaguChek XS and InRatio2 PT/INR. The INRatio2 PT/INR was withdrawn from the market in October 2016 and is not currently
Evidence-based recommendations on transvaginal mesh repair of anterior or posterior vaginal wall prolapse. This involves inserting a mesh to replace tissue that has weakened and caused the pelvic organs to drop down (prolapse) into the vagina. This guidance replaces NICE interventional
Evidence-based recommendations on transcutaneous microwave ablation for severe primary axillary hyperhidrosis in adults. This involves using microwaves to destroy sweat glands in the armpit.
Evidence-based recommendations on artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure. This involves replacing the 2 lower chambers of the heart with a mechanical device to improve circulation until heart transplantation.
Evidence-based recommendations on subcutaneous implantable cardioverter defibrillator insertion for preventing sudden cardiac death. This involves placing a device under the skin of the chest, which detects and treats fast heartbeats called tachyarrhythmias. This guidance replaces NICE interventional procedures guidance on insertion
This guideline covers diagnosing, monitoring and managing asthma in adults, young people and children. It aims to improve the accuracy of diagnosis, help people to control their asthma and reduce the risk of asthma attacks. It does not cover managing
This guide outlines the process to be followed when police bring a person to the Emergency Department under a section136 of the Mental Health Act and the responsibilities of the different agencies caring for the person. It notes the main change detailed
Evidence-based recommendations on atezolizumab (Tecentriq) for locally advanced or metastatic urothelial carcinoma in adults. This guidance only includes recommendations for untreated urothelial carcinoma when cisplatin-based chemotherapy is unsuitable. NICE are developing separate guidance for urothelial carcinoma that has progressed after platinum-containing chemotherapy.
This report addresses the extremely important area of epilepsy in the field of intellectual disability (ID), also known as learning disability. Epilepsy and ID are two conditions that carry stigma and can lead to social isolation. An individual who experiences
This guideline covers identifying and managing depression in children and young people aged between 5 and 18 years. Based on the stepped care model, it aims to improve recognition and assessment and promote effective treatments for mild, moderate and severe
This guideline sets out how health and social care staff can support people to be independent following a hospital stay or when daily life at home becomes too difficult. It covers how to assess intermediate care needs, including setting goals with the person
This guidance is aimed at DH group bodies (including CCGs, NHS trusts, NHS foundation trusts and arm’s length bodies) to help them complete their statutory annual reports and accounts for 2017 to 2018.
Evidence-based recommendations on SecurAcath for securing percutaneous catheters. NICE has published a medtech innovation briefing on SecurAcath for an emerging indication (securing cerebrospinal fluid catheters) for which the evidence and use are still developing.